Overview of Picked Chemical Compounds and Intermediates
Overview of Picked Chemical Compounds and Intermediates
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one. Pharmaceutical Intermediates
Bortezomib Acid Impurity: This really is an impurity relevant to bortezomib, a proteasome inhibitor Employed in the treatment method of various myeloma. Its synthesis or examine is crucial for making sure the purity and safety of your drug.
Abiraterone Acetate Intermediate (CAS NO. 122111-01-seven): A precursor within the synthesis of abiraterone acetate, a drug used in the therapy of prostate most cancers by inhibiting androgen generation.
Imatinib Intermediate (CAS NO. 152460-ten-1): A crucial compound while in the synthesis of imatinib, a drug that targets certain forms of cancer, such as Long-term myelogenous leukemia (CML).
Docetaxel Intermediate: A compound used in the synthesis of docetaxel, a chemotherapy medication that treats various cancers for example breast, lung, and prostate cancer.
two. Chemical Impurities and Byproducts
GeMcitabine Intermediates (T6, T9, eight): These are definitely intermediates in the synthesis of gemcitabine, an anti-most cancers drug. Their examine is vital for optimizing the creation system and making sure significant purity.
Lapatinib Intermediate (CAS NO. 231278-eighty four-five): Lapatinib is applied to treat breast cancer, and these Androsta-5 intermediates are linked to its creation.
Fulvestrant Intermediates: Fulvestrant is undoubtedly an estrogen receptor antagonist Utilized in the therapy of breast cancer. Several intermediates help in the synthesis of this drug.
Paclitaxel Side Chain Acid (CAS NO. 949023-16-9): This intermediate is Employed in the synthesis of paclitaxel, a chemotherapy drug powerful in managing cancers like ovarian, breast, and lung cancer.
3. Other Notable Compounds
Irinotecan Hydrochloride Trihydrate (CAS NO. 136572-09-3): A chemotherapy drug Utilized in the cure of colorectal most cancers and small mobile lung most cancers.
three-Amino-1-hydroxyadamantane (CAS 702-eighty two-9): This compound is linked to the synthesis of adamantane derivatives, that Abiraterone Acetate Intermediate have different purposes, which include antiviral Qualities.
Vildagliptin Intermediates: Utilized in the production of vildagliptin, an oral drug for kind two diabetic issues that inhibits the enzyme DPP-4 to regulate blood sugar levels.
four. Miscellaneous Compounds
D-Gluconic Acid δ-Lactone (CAS NO. 61259-forty eight-1): This compound is involved with the synthesis of various gluconic acid derivatives, that are used in food, pharmaceutical, and industrial purposes.
Canagliflozin Intermediate 2: A precursor from the synthesis of canagliflozin, a medication employed to handle type 2 diabetes by inhibiting sodium-glucose co-transporter 2 (SGLT2).